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Profiles

Epidemiology

 

Name and title: Anne Ahrendt Bjerregaard, MSc Human Nutrition, PhD student

Affiliation: Department of Epidemiology Research, Statens Serum Institut

Pillar: Epidemiology

Research topic(s) and interests: Research topics: Validation and reliability of a food frequency questionnaire (FFQ) for assessing dietary intake in Danish adolescents: compared with 24-hour recalls and biomarkers.
Impact of maternal dietary habits during pregnancy on dietary habits of the offspring at age 14 years.

Interests: Nutrition, dietary assessment methods, validation, reproducibility, biomarkers, food composition tables, study design, data collection, determinants of adolescent dietary habits, impact of nutrition on health in adolescents.

Research methods: FFQ, 24-hour recalls, data from FFQ’s completed by mothers in DNBC


Name and title: Susanne Hansen, cand.scient.san.publ, PhD student

Affiliation: Department of Epidemiology Research, Statens Serum Institut

Pillar: Epidemiology

Research topic(s) and interests: Perinatal epidemiology, diet during pregnancy and risk of offspring asthma and allergic disease.

Research methods: Register data, birth cohort data


Ekaterina Maslova

Name and title: Ekaterina Maslova, ScD, postdoc.

Affiliation: Department of Epidemiology Research, Statens Serum Institut

Pillar: Epidemiology

Research topic(s) and interests: fetal programming; maternal dietary exposures and dietary patterns during pregnancy (self-reported and biomarkers) and child allergic, respiratory, and metabolic disease development; dietary influences on epigenetic modifications.

Research methods: prospective cohorts and clinical trials, multivariate linear/logistic/log-binomial/log-Poisson regression, spline regression, macronutrient substitution models, multiple imputations/IPW 


Name and title:  Marin Strøm, PhD, postdoc.

Affiliation: Centre for Fetal Programming, Dept. Epidemiology Research, Statens Serum Institut 

Pillar: Epidemiology

Research topic(s) and interests: Maternal and child/adolescent health and development in relation to exposures during pregnancy/fetal life/early life.

Research methods: Observational prospective cohort studies, registry based follow up of randomized controlled trials with fish oil.

Comments: Primary interest regarding maternal health is perinatal/postpartum depression and cardiovascular diseases and cancer in women in the years after childbearing. Concerning child/adolescence health and development focus is on psychiatric and behavioral outcomes as well as school performance and other developmental outcomes.

 


Animal experimental and cell physiology

 

Name and title: Anjana Anita Nalla, MSc, PhD student

Affiliation: Beta cell biology, (Jens Høiriis Nielsen), Faculty of Health and Medical Sciences (SUND), University of Copenhagen

Pillar: Animal experimental and cell physiology

Research topic(s) and interests: Alpha 1-antitrypsin effect on islets from LPS induced inflammation.

Research methods: Murine Islet isolation, apoptosis, multiplex suspension array

 


 

Name and title: Anne Marie Dixen Axel, PhD student

Affiliation: Department of Clinical Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, Copenhagen University

Pillar: Animal experimental and cell physiology

Research topic(s) and interests: Animal models for human disease, fetal programming, obesity and diabetes, metabolic syndrome, small intestine, gastric bypass operations.

Research methods: qPCR, histology, ELIZA of blood plasma, experimental work with sheep, plan on doing western blot

 


 

Name and title: Caroline Jaksch, PhD student

Affiliation: Beta cell biology, (Jens Høiriis Nielsen group), Faculty of Health and Medical Sciences (SUND), University of Copenhagen.

Pillar: Animal experimental and cell physiology

Research topic(s) and interests: Maternal malnutrition and fetal programming, epigenetics, metabolic syndrome, type 2 diabetes, β-cell mass and regeneration.

Methods used: Levin DR/DIO rat model, Microarray, Q-PCR, IHC


 

Name and title: Lea Hüche Larsen, PhD student

Affiliation: Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen

Pillar: Animal experimental and cell physiology

Research topic(s) and interests: Fetal programming by maternal diet, skeletal muscles, cellular models for fetal programming, metabolism, taurine.

Research methods: Cell culture, animal models, biochemical assays, mitochondrial oxidation, qPCR, WB, ELISA.

 


 

Name and title: Lærke Johnsen, cand. agro, PhD student

Affiliation: Department of Clinical Veterinary and Animal Science, University of Copenhagen

Pillar: Animal experimental and cell physiology

Research topic(s) and interests: Fetal metabolic programming and the hypothalamic-pituitary-thyroidal axis, animal models for human disease

Methods used: Sheep model including late gestation programming via overnutrition or undernutrition, and early postnatal overnutrition. Data obtained mainly by metabolic challenge tests, qRT-PCR and histology.


Name and title: Prabhat Khanal, MSc, PhD student

Affiliation: University of Copenhagen, Faculty of Health and Medical Sciences, Department of Veterinary Clinical and Animal Sciences

Pillar: Animal experimental and cell physiology

Research topic(s) and interests: Fetal programming of early onset of metabolic disorders in sheep.

Research methods: In-vivo challenge tests, qPCR, histology, immunohistochemistry, ELISA

 


Name and title: Sasan Nazemi, PhD student 

Affiliation: Department of Clinical veterinary medicine and animal sciences, SUND/KU

Pillar: Animal experimental and cell physiology

Research topic(s) and interests: Lactation physiology and pathology, animal experiments especially murine models, acute phase response, aquaporins, mastitis both in humans and animals.

Research methods: Proteomics, IHC, WB, qPCR

  


 

Name and title: Amarnadh Nalla, Postdoc

Affiliation: Beta cell biology, (Jens Høiriis Nielsen group), Faculty of Health and Medical Sciences (SUND), University of Copenhagen

Pillar: Animal experimental and cell physiology

Research topic(s) and interests: Beat cell mass and function during the pregnancy and various pathophysiological conditions. 
Research methods: Rodent Islet isolation, beta cell culture, proliferation, apoptosis, chromatography, proteomic, multiplex suspension array and several biochemical methods.


Clinical physiology

 

Name and title: Amalie Ribel-Madsen, MSc Eng, Systems Biology.

Affiliation: Department of Systems Biology, Technical University of Denmark, and Department of Endocrinology, Diabetes and Metabolism, Copenhagen University Hospital.

Pillar: Clinical physiology

Research topics and interests: Fetal programming, type 2 diabetes, metabolomics, lipidomics.
Research methods: HPLC-MS 


Name and title: Linn Gillberg, MSc, PhD student

Affiliation: Diabetes and Metabolism, Department of Endocrinology, Rigshospitalet

Pillar: Clinical physiology

Research topic(s) and interests: Epigenetics, low birth weight, high-fat overfeeding, fasting

Research methods: Genome-wide and gene specific DNA methylation and gene expression analyses including microarrays, pyrosequencing and qPCR

 


 

Name and title: Ninna Schultz, MSc Human biology, PhD student

Affiliation: Diabetes and Metabolism (with Allan Vaag), Rigshospitalet

Pillar: Clinical physiology

Research topic(s) and interests:
My research area includes two cohorts: adult subjects born with low birth weight and adult offspring of mothers with gestational diabetes.
My focus is:  the effect of fetal programming on muscle and fat stem cell function. More specific:
- Muscle and fat stem cell proliferation and differentiation potential
- Muscle and fat stem cell metabolism (insulin signaling, glucose uptake, lipolysis, lipogenesis)
- The endocrine function of fat stem cells

Research methods: Human studies, isolating of stem cells from biopsies, cell culturing of adipocytes and myocytes, western Blotting, qPCR, microRNA assay and protein detection by MSD. Soon tracer studies in primary stem cell cultures.

 


 

Name and title: Charlotte Brøns, MSc (Human Nutrition), PhD (Low birth weight and high-fat overfeeding in the pathophysiology of type 2 diabetes – metabolic, genetic transcriptional and epigenetic aspects), postdoc.

Affiliation: Dept. of Endocrinology (Diabetes and Metabolism), Rigshospitalet

Pillar: Clinical physiology

Research topic(s) and interests: The impact of low birth weight and fetal malnutrition on risk of developing adiposity, insulin resistance and metabolic disease in human subjects, with special focus on understanding the molecular underlying mechanisms.

Research methods: Hyperinsulinemic euglycemic clamp with glucose tracer (3-3H-glucose), OGTT, IVGTT, meal-test, indirect calorimetry (ventilated hood), DEXA, 31P Nuclear Macnetic Spectroscopy (NMR/MRS), 24-hr energy expenditure (respiratory chambers), substrate oxidation rate, diet induced thermogenesis (DIT).

 


 

Name and title: Christa Broholm, postdoc.

Affiliation: Diabetes and Metabolism, Rigshospitalet

Pillar: Clinical physiology

Research topic(s) and interests: Human muscle and fat stem cells, epigenetics, type 2 diabetes

Research methods: culture of human fat and muscle cells, pyrosequencing, global DNA methylation arrays, PCR, western blotting, chip sequencing

 


 

Name and title: Louise Groth Grunnet, MSc, PhD, postdoc.

Affiliation: Diabetes & Metabolism, Rigshospitalet

Pillar: Clinical physiology

Research topic(s) and interests: Intrauterine programming, The impact of low birth weight on later risk of developing type 2 diabetes and obesity, Developmental programming of body composition, The impact of low birth weight in developing countries (India), Gestational diabetes – the consequences for mother and child. All studies have been in humans.

Research methods: In vivo: Hyperinsulinemic euglycemic clamp, intravenous glucose tolerance test, indirect calorimetry, DEXA scanning, oral glucose tolerance test
Some experience in: NMR spectroscopy data, muscle and fat biopsies, questionnaires.

 

Last revised 9 March 2015